ANSA BIOTECHNOLOGIES

Importer · United States

Biotechnology / Synthetic Biology

About ANSA BIOTECHNOLOGIES

Ansa Biotechnologies, Inc., founded in 2018 as a spinout from the University of California, Berkeley, is commercializing novel enzymatic DNA synthesis technology. The technology is based on a polymerase, terminal deoxynucleotidyl transferase (TdT), which doesn’t require a template to synthesize DNA. Ansa conjugates a single nucleotide to the TdT enzyme. The enzyme remains covalently attached to the DNA after it adds this nucleotide and is subsequently cleaved off prior to the next nucleotide addition. This process results in a slightly modified base on the newly synthesized DNA, and also uses up the enzyme at each cycle. Based on this, the initial applications of the process may include those that only require a small amount of DNA such as PCR primers.